mkin, branch nlmixrFitting kinetic models to chemical degradation data (also on github)https://erac.jrwb.de/mkin/atom?h=nlmixr2022-01-11T18:57:58ZUpdate static docs2022-01-11T18:57:58ZJohannes Rankejranke@uni-bremen.de2022-01-11T18:57:58Zurn:sha1:c0638c84568d475b3b059e2c6e593e6f03b846bcUpdate the dimethenamid vignette with current saemix2022-01-11T18:28:22ZJohannes Rankejranke@uni-bremen.de2022-01-11T18:28:22Zurn:sha1:e7751e791f46b2aa334f52109e0bd8211dfd7083
Convergence is faster with this version (@ecomets mentioned that there
was a bugfix lately that could lead to faster convergence). However,
if I use too many iterations (i.e. 10 000 as in the last version of
this vignette), I get an error in solving omega.teta during later
iterations, apparently due to overparameterisation of the DFOP model
in this case.
PD in Freiburg statt Bremen2021-12-08T08:28:06ZJohannes Rankejranke@uni-bremen.de2021-12-08T08:28:06Zurn:sha1:ad9e027acef8eeeb463dc38ffe81acc0e1351c72Update required saemix version, update tests2021-11-17T11:59:49ZJohannes Rankejranke@uni-bremen.de2021-11-17T11:59:49Zurn:sha1:d75378911cef79b3ed95daef71bf67db413d2ac8Use the official master branch of saemix2021-11-17T10:13:33ZJohannes Rankejranke@uni-bremen.de2021-11-17T10:13:33Zurn:sha1:e83e7c7c0aec23132a1a15c54cb8a8e0fe104ceb
As my changes were merged meanwhile
Update CAKE URL2021-11-17T09:39:39ZJohannes Rankejranke@uni-bremen.de2021-11-17T09:39:39Zurn:sha1:85c2a93011181af482bd918d929bfb18741e71beRound initial population values for nlmixr2021-10-08T12:48:20ZJohannes Rankejranke@uni-bremen.de2021-10-08T12:38:19Zurn:sha1:648637a60a9991cdc8d8d7cbe481cac7f36c953c
This avoids numerical instabilities that sometimes occur with the FOCEI
algorithm in nlmixr when the initial values are very close to the
optimum values
Replace outdated JSS article URL by doi2021-10-06T05:38:32ZJohannes Rankejranke@uni-bremen.de2021-10-06T05:38:32Zurn:sha1:aa36fb0c8000df44abb635c9ab490f478e0775b1
Thanks to the hint of Achim Zeileis from the CRAN team
Update docs2021-10-05T15:33:52ZJohannes Rankejranke@uni-bremen.de2021-10-05T15:33:52Zurn:sha1:ff83d8b2ba623513d92ac90fac4a1b0ec98c2cb5Fix nlmixr for logit transformed parameters2021-10-05T14:55:41ZJohannes Rankejranke@uni-bremen.de2021-10-05T14:55:41Zurn:sha1:121e38654eea03c91aa117da58fc342feff01756